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Glossary
Other Surgery Options
In the early 1990s, roughly 30 percent of prostate cancer
patients in the United States were treated by surgery, 30
percent by radiation, and 20 percent by watchful waiting.
(Most of the rest were treated with a combination of
therapies). In Europe, by contrast, watchful waiting
constitutes the standard treatment for asymptomatic prostate
cancer.
The popularity of surgery in this country has grown
tremendously in recent years. A study of Medicare patients'
records found that the number of men nationwide receiving
radical prostatectomy by 1990 was six times greater than the
number recorded for 1984, and the increase was seen in all
age groups, from the youngest (that is, age 65) to men in
their eighties.
The growth of the popularity of surgery has corresponded
with the advent of minimally invasive surgical options that
reduce side effects and promote faster recovery times. Two
surgical options touched on in this section are radical
prostatectomy and cryosurgery.
Radical Prostatectomy
An operation called radical prostatectomy completely removes
the prostate and nearby tissues. A radical prostatectomy is
further described in terms of the incisions used by the
surgeon to reach the gland. In a retropubic prostatectomy,
the prostate is reached through an incision in the lower
abdomen; in a perineal prostatectomy, the approach is through
the perineum, the space between the scrotum and the anus.
In radical prostatectomy, the surgeon excises the entire
prostate gland, along with both seminal vesicles, both
ampullae (the enlarged lower sections of the vas deferens),
and other surrounding tissues. The section of urethra that
runs through the prostate is cut away (and with it some of
the sphincter muscle that controls the flow of urine). Pelvic
lymph node dissection is done routinely as part of a
retropubic prostatectomy; with a perineal prostatectomy,
lymph node dissection requires a separate incision.
Cryosurgery
Cryosurgery uses liquid nitrogen to freeze and kill prostate
cancer cells. Guided by TRUS, the doctor places needles in
preselected locations in the prostate gland. The needle
tracks are dilated for the thin metal cryo probes to be
inserted through the skin of the perineum into the prostate.
Liquid nitrogen in the cryo probes forms an ice ball that
freezes the prostate cancer cells; as the cells thaw, they
rupture. The procedure takes about 2 hours, requires
anesthesia (either general or spinal), and requires 1 or 2
days in the hospital.
During cryosurgery, a warming catheter inserted through
the penis protects the urethra, and incontinence is seldom a
problem. However, the overlying nerve bundles usually freeze,
so most men become impotent.
The appearance of prostate tissue in ultrasound images
changes when it is frozen. To be sure enough prostate tissue
is destroyed without too much damage to nearby tissues, the
surgeon carefully watches these images during the procedure.
A suprapubic catheter is placed through a skin incision on
the abdomen into the bladder so that if the prostate swells
after the procedure (which usually occurs), it won't block
the passage of urine. The catheter is removed 1 to 2 weeks
later.
After the procedure, there will be some bruising and
soreness of the area where the probe was inserted. You will
likely stay in the hospital for 1 or 2 days. Cryosurgery is
less invasive than radical prostatectomy, so there is less
blood loss, a shorter hospital stay, shorter recovery period,
and less pain than radical surgery. But compared with surgery
or radiation therapy, doctors know much less about the
long-term effectiveness of cryosurgery.
Current techniques using ultrasound guidance and precise
temperature monitoring have only been available for a few
years. Outcomes of long-term (10- to 15-year) follow-up must
still be collected and analyzed. For this reason, most
doctors do not include cryotherapy among the options they
routinely consider for initial treatment of prostate cancer.
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